Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody
Thermo Fisher Scientific의 BAIAP2L1 Polyclonal Antibody는 인간 BAIAP2L1 단백질을 인식하는 토끼 다클론 항체입니다. Western blot, IHC(P), ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BAIAP2L1 (Product #RP-92592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638460 |
Product Specific Information
Immunogen sequence:
ERSNVVRKDY DTLSKCSPKM PPAPSGRAYT SPLIDMFNNP ATAAPNSQRV NNSTGTSEDP SLQRSVSVAT GLNMMKKQKV KTIFPHTAGS N
Highest antigen sequence identity:
- Mouse: 83%
- Rat: 79%
Target Information
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided into two groups, IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.
The encoded protein contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac, participating in signal transduction pathways that link plasma membrane deformation and actin cytoskeleton remodeling.
Overexpression promotes actin assembly and membrane protrusions in mammalian cells and is essential for forming a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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