Thermo Fisher Scientific LONP1 Polyclonal Antibody
Thermo Fisher Scientific의 LONP1 Polyclonal Antibody는 인간 LONP1 단백질을 인식하는 토끼 IgG 항체입니다. Western blot과 ICC/IF에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 미토콘드리아 단백질 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human LONP1. Recombinant protein control fragment (Product #RP-108177) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856062 |
Product Specific Information
Immunogen sequence:
PAEVLMVEVE NVVHEDFQVT EEVKALTAEI VKTIRDIIAL NPLYRESVLQ MMQAGQRVVD NPIYLSDMGA ALTGAESHEL QDVLEETNIP KRLYKALSLL KKEFELSKLQ QRLGREVEEK IKQTHRKYLL QEQLKIIKKE LGLEKDDKDA
Target Information
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. It mediates selective degradation of misfolded, unassembled, or oxidatively damaged polypeptides in the mitochondrial matrix. It may also function as a chaperone in the assembly of inner membrane protein complexes and participate in the regulation of mitochondrial gene expression and maintenance of mitochondrial genome integrity. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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