Thermo Fisher Scientific MOV10L1 Polyclonal Antibody
MOV10L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P) 등에서 사용 가능. 고순도 항원 친화 크로마토그래피로 정제된 액상 시약으로, 안정적인 장기 보관 가능.
- 카탈로그번호
- PA553898
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MOV10L1. Recombinant protein control fragment (Product #RP-92345) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644067 |
Product Specific Information
Immunogen sequence:
EYISYVTEIH EEDVTLKINP EFEQAYNFEP MDVEFTYNRT TSRRCHFALE HVIHLGVKVL FPEEIILQSP QVTGNWNHAQ DTKSSGQSTS KKNRKTMTDQ
- Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 85%
Target Information
Isoform 1:
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, essential for germline integrity. Acts via the piRNA metabolic process forming complexes with piRNAs and Piwi proteins to repress transposons. Specifically binds to piRNA precursors and promotes generation of intermediate piRNA processing fragments loaded to Piwi proteins. Displays 5′–3′ RNA unwinding activity.
Isoform 2:
May act downstream of MEF2C during heart formation. Functions as a cardiac-specific suppressor of cardiomyocyte hypertrophy and cell cycle progression, potentially through regulation of CDKN1A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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