Thermo Fisher Scientific XRCC1 Monoclonal Antibody (OTI2H8), TrueMAB
Human XRCC1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2H8). Western blot에 적합하며, DNA 손상 복구 관련 연구에 활용. Lyophilized 형태, 1 mg/mL 농도, PBS buffer(8% trehalose) 기반. -20°C 보관, 동결-해동 반복 피함.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H8 |
| Immunogen | Full length human recombinant XRCC1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
XRCC1 (X-ray cross complementing factor-1) participates in DNA base excision repair.
It is a 70 kDa protein that interacts with DNA repair enzymes such as poly (ADP-ribose) polymerase (PARP), DNA ligase III, and DNA polymerase beta.
XRCC1 contains a BRCT domain (BRCA1 C-terminus domain) that mediates protein-protein interactions, including with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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