Thermo Fisher Scientific PSMB3 Polyclonal Antibody
Thermo Fisher Scientific의 PSMB3 Polyclonal Antibody는 인간에 반응하며 Western blot 및 IHC(파라핀) 분석에 적합합니다. Goat IgG 기반의 비결합 항체로, 0.5 mg/mL 농도의 액상 형태이며 TBS 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (NLYELKEGRQ) corresponding to the internal amino acids of PSMB3 (aa 72–82) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10983411 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits. Two rings are composed of 7 alpha subunits and two rings of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
An essential function of the immunoproteasome is the processing of class I MHC peptides. The PSMB3 gene encodes a member of the proteasome B-type family (T1B family), a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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