Thermo Fisher Scientific SYT12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SYT12. Recombinant protein control fragment (Product #RP-90446). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SYT12,uniProtId:Q8IV01-1,ncbiNodeId:9606,antigenRange:288-418,antigenLength:421,antigenImageFileName:PA5-52771_SYT12_Q8IV01-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52771_SYT12_Q8IV01-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648158

Product Specific Information

Immunogen sequence: LLSLSYLPTA ERLTVVVVKA KNLIWTNDKT TADPFVKVYL LQDGRKMSKK KTAVKRDDPN PVFNEAMIFS VPAIVLQDLS LRVTVAESSS DGRGDNVGHV IIGPSASGMG TTHWNQMLAT LRRPVSMWHA V

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.

Target Information

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.