Thermo Fisher Scientific LETM1 Polyclonal Antibody
LETM1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. Human 시료 반응성이 있으며 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer(40% glycerol)로 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LETM1. Recombinant protein control fragment (Product #RP-90425). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643347 |
Product Specific Information
Immunogen sequence:
SKTGEEKYVE ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVAEI VATLE
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 79%
Target Information
This gene encodes a protein localized to the inner mitochondrial membrane. It functions to maintain mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15, and 19.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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