Thermo Fisher Scientific HYD Polyclonal Antibody
Thermo Fisher Scientific의 HYD Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며, EDD 단백질의 내인성 수준을 검출합니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UBR5 (Accession O95071), corresponding to amino acid residues M1–E44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818121 |
Product Specific Information
Antibody detects endogenous levels of total EDD.
Target Information
EDD (E3 identified by Differential Display) is a progestin-regulated gene isolated from T-47D human breast cancer cells. It is a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor required for imaginal disc growth control.
EDD contains a HECT domain at the carboxy terminus. HECT domain-containing proteins act as ubiquitin-protein ligases (E3 enzymes). EDD binds to ubiquitin and, like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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