Thermo Fisher Scientific TXNL4B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human TXNL4B. Recombinant protein control fragment (Product #RP-107462). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TXNL4B,uniProtId:Q9NX01-1,ncbiNodeId:9606,antigenRange:2-71,antigenLength:149,antigenImageFileName:PA5-66805_TXNL4B_Q9NX01-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66805_TXNL4B_Q9NX01-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664960

Product Specific Information

Immunogen sequence: SFLLPKLTSKK EVDQAIKSTA EKVLVLRFGR DEDPVCLQLD DILSKTSSDL SKMAAIYLVD VDQTAVYTQ

Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.

Target Information

Dim2, also known as TXNL4B (thioredoxin-like 4B), or DLP, is a 149 amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. Evolutionarily related and sharing 38% sequence identity with Dim1, Dim2 is required for S/G(2) transition during the cell cycle and is able to bind the PRP6 (U5-102K) subunit of the spliceosome. The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn`s disease, which is a gastrointestinal inflammatory condition.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.