Thermo Fisher Scientific CD19 Polyclonal Antibody
CD19 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 시료에 반응. WB, IHC, Flow Cytometry, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Flow Cytometry (Flow) | 0.2 µg / 1×10⁶ cells |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CD19, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and appears on certain myeloid leukemia cells, particularly of monocytic lineage. CD19 is the earliest and broadest B cell-restricted antigen and serves as a functional regulator of normal and malignant B cell proliferation. It plays a critical role in antigen receptor-dependent stimulation by lowering the activation threshold and can signal independently of BCR co-ligation. Mutations in CD19 lead to hypogammaglobulinemia, while overexpression results in B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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