Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
TRAF3IP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–223 of Human TRAF3IP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547981 |
Product Specific Information
- Recommended positive controls: U87-MG, mouse testis, rat testis
- Predicted reactivity: Bovine (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation, and apoptosis in various cell types. TNFR-associated factors (TRAFs) are a family of proteins that act as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region essential for downstream signaling. MIP-T3 associates with TRAF3, binds to taxol-stabilized microtubules and tubulin in vitro, and recruits TRAF3 to microtubules when both are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3, suggesting a mechanism for sequestering TRAF3 to the cytoskeletal network.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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