Thermo Fisher Scientific Phospho-Rb (Ser807) Recombinant Rabbit Monoclonal Antibody (1T3E10)
Rb 단백질의 Ser807 인산화 부위를 특이적으로 인식하는 재조합 토끼 단클론 항체. Western blot 및 ELISA에 적합. 인간, 마우스, 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제. -20°C 보관, 동결/해동 회피.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1T3E10 |
| Immunogen | A synthetic phosphorylated peptide around S807 of human RB (P06400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3) with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912094 |
Product Specific Information
- Target localization: Nucleus
- Immunogen sequence: YISPL
Target Information
Rb (Retinoblastoma protein) is a tumor suppressor nuclear phosphoprotein that binds DNA and is phosphorylated on serine and threonine residues. It forms complexes with SV40 large T antigen, adenovirus E1A, and HPV-16 E protein. Rb regulates transcription, and loss of its function can lead to uncontrolled cell growth. Mutations or aberrations in the RB gene are associated with various cancers including breast, colon, prostate, kidney, nasopharyngeal carcinoma, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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