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Thermo Fisher Scientific Phospho-p95 NBS1 (Ser343) Polyclonal Antibody
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Phospho-p95 NBS1 (Ser343) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Protein A 정제, 1 mg/mL 농도, -20°C 보관. DNA 이중가닥 절단 복구 및 세포주기 체크포인트 연구용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 04:32
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Thermo Fisher Scientific BS-6125R Phospho-p95 NBS1 (Ser343) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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590,500원VAT 포함 649,550원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-p95 NBS1 (Ser343) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human NBS1 around the phosphorylation site of Ser343 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. This indicates a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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