Thermo Fisher Scientific GPD2 Polyclonal Antibody
Thermo Fisher Scientific의 GPD2 Polyclonal Antibody는 인간 GPD2 단백질을 인식하는 rabbit polyclonal 항체로, Western blot 및 IHC(P) 적용 가능. 고순도 항원 친화 크로마토그래피로 정제되었으며, 안정적인 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPD2. Recombinant protein control fragment (Product #RP-102982) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642140 |
Product Specific Information
Immunogen sequence:
TAVDMISRRT RLAFLNVQAA EEALPRIVEL MGRELNWDDY KKQEQLETAR KFLYYEMGYK SRSEQLTDRS EISLLPSDID RYKKRFHKFD ADQKGFITIV DVQRVLESIN VQMDENTL
Ortholog sequence identity:
- Mouse: 90%
- Rat: 86%
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1.1.99.5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of enzyme-bound FAD.
Together with cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which transfers reducing equivalents into mitochondria, resulting in reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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