Thermo Fisher Scientific GNB3 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal GNB3 항체로 Western Blot, ICC/IF, ELISA에 사용 가능. Recombinant GNB3(aa 1-340)로부터 유래된 면역원 사용. 액상 형태, 0.94 mg/mL 농도, PBS/glycerol buffer에 보관. -20°C에서 보관하며 동결-해동 반복 피함.
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Thermo Fisher Scientific GNB3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–340 of human GNB3 (NP_0020661) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855191 |
Product Specific Information
Immunogen sequence:
MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN AICFFPNGEA ICTGSDDASC RLFDLRADQE LICFSHESII CGITSVAFSL SGRLLFAGYD DFNCNVWDSM KSERVGILSG HDNRVSCLGV TADGMAVATG SWDSFLKIWN
Target Information
Heterotrimeric guanine nucleotide-binding proteins encoded by this gene are associated with essential hypertension and obesity. The GNB3 polymorphism is linked to the occurrence of the splice variant GNB3-s, which shows increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside the splice donor and acceptor sites. Additional splice variants may exist but have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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