Thermo Fisher Scientific beta-2 Microglobulin Polyclonal Antibody
Human beta-2 Microglobulin을 인식하는 Goat Polyclonal Antibody로 Western blot 및 Peptide ELISA에 적합. 0.5 mg/mL 농도의 액상 형태이며, TBS buffer(pH 7.3, 0.5% BSA)로 안정화. 연구용으로 항원 처리 및 MHC Class I 관련 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific beta-2 Microglobulin Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RIEKVEHSDLSFSKD (aa 65–79) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933540 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
Beta-2-microglobulin (B2M) is a 12–14 kDa protein that is a subunit of the major histocompatibility complex (MHC) class I.
Human beta-2 Microglobulin associated with HLA Class I antigens is expressed on many cell types including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells, but is absent on erythrocytes.
Beta-2-microglobulin is also found in free form in the plasma. Its amino acid sequence is homologous to the constant regions of immunoglobulin heavy and light chains, with a predominantly beta-pleated sheet structure.
The protein is ubiquitously expressed in the cytoplasm and is involved in antigen processing and presentation. It also plays a role in TCR signaling and downstream signaling in naive CD8+ cells.
The B2M gene is located on chromosome 15, and mutations can result in hypercatabolic hypoproteinemia.
Beta-2-microglobulin levels can be used to assess renal function in kidney transplant recipients and serve as a prognostic marker for HIV infection.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.