
Thermo Fisher Scientific GRIPAP1 Monoclonal Antibody (OTI1F4), TrueMAB
인간 GRIPAP1 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. PBS(8% trehalose) 버퍼에 용해 가능하며, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F4 |
| Immunogen | Full length human recombinant protein of human GRIPAP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PDZ domain-containing proteins such as PSD-95 and GRIP play key roles in glutamate receptor plasticity.
GRIP-associated proteins (GRASPs) bind to distinct PDZ domains within GRIP and regulate glutamate receptor function.
GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000).
Research suggests GRASP-1 regulates neuronal ras signaling and contributes to AMPA receptor distribution via NMDA receptor activity (Ye et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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