
Thermo Fisher Scientific CXCL13 Polyclonal Antibody
Thermo Fisher Scientific의 CXCL13 Polyclonal Antibody는 마우스 CXCL13 단백질을 인식하는 Rabbit IgG 항체로, WB 및 IHC(F) 실험에 적합합니다. Protein A로 정제된 액상 형태이며 1 mg/mL 농도로 제공됩니다. CXCL13 관련 면역반응 연구 및 HIV 항체 생성 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000
- Publications: Refer to references component
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: —
- Publications: 2 available (see references)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein - mouse CXCL13 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2086059 |
Product Specific Information
- Recommended positive controls: CXCL13 transfected supernatant
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles of the spleen, lymph nodes, and Peyer’s patches.
Produced by macrophages, with high expression in large peritoneal macrophages, Kupffer cells, and lung macrophages (CD11c+ and CD11c−).
The cellular ligand for CXCL13 is CXCR5 (Burkitt’s Lymphoma Receptor 1), expressed on B cells, Tfh cells, and some memory T cell populations.
CXCL13 plays an important role in chronic lymphocytic leukemia (CCL) development and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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