Thermo Fisher Scientific ELOA3 Polyclonal Antibody
ELOA3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 Immunocytochemistry에 사용 가능. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며 -20°C에서 안정적 저장 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ELOA3 (Accession Q8NG57), corresponding to amino acid residues A383–K433 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850768 |
Product Specific Information
Antibody detects endogenous levels of total ELOA3.
Target Information
The elongin (SIII) complex is composed of a transcriptionally active A subunit and two small regulatory subunits, B and C. This complex stimulates the transcription elongation rate of RNA polymerase II by suppressing time spent at template-encoded arresting sites along DNA.
Elongin A3, also known as RNA polymerase II transcription factor SIII subunit A3 and Transcription elongation factor B polypeptide 3C, is a 546 amino acid nuclear protein that functions as a general transcription elongation factor that increases RNA polymerase II transcription elongation and forms a stable complex with Elongin BC.
In contrast to Elongin A, transcriptional activity of Elongin A3 is not stimulated by Elongin BC. Elongin A3 contains one TFIIS N-terminal domain and is ubiquitously expressed in human tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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