Thermo Fisher Scientific K-cadherin Polyclonal Antibody
Thermo Fisher Scientific의 K-cadherin Polyclonal Antibody는 인간 K-cadherin 단백질을 인식하는 토끼 유래 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 20% 글리세롤을 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 325–606 of Human K-cadherin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.0, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547458 |
Product Specific Information
- Recommended positive controls: H1299, HCT116
- Predicted reactivity: Mouse (97%), Rat (98%), Chicken (85%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cadherins constitute a family of transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions. Members of this family are differentially expressed in various tissues and play roles in maintaining tissue integrity and morphogenesis.
Cadherins are divided into type I and type II subgroups:
- Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II cadherins: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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