Thermo Fisher Scientific BNIP2 Polyclonal Antibody
BNIP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능하며 인간 및 설치류 반응성. 고순도 항원 친화 크로마토그래피 정제, 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific BNIP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 6–229 of Human BNIP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547451 |
Product Specific Information
- Recommended positive controls: Jurkat, Raji, NCI-H929
- Predicted reactivity: Mouse (91%), Rat (92%), Zebrafish (80%), Xenopus laevis (86%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BNIP-2 (previously designated Nip2 and Nip21 in human and mouse respectively) shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP).
Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby mediating signaling pathways involving receptor kinases, small GTPases, and apoptotic proteins.
Nix (also designated Nip3L or Bnip3L) is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항원 이미지: PA5-29977_BNIP2_Q12982-1_Rabbit.svg, PA5-29977_BNIP2_Q12982-1_Rabbit_PDP.jpeg)
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