ELK Biotechnology DUOX1 rabbit pAb

제품명

DUOX1 rabbit pAb

제품 개요

DUOX1 단백질을 인식하는 토끼 유래 폴리클로날 항체로, Western Blot(WB) 분석에 적합합니다. 인간 및 랫트 시료에서 반응성을 보이며, NADPH oxidase 계열 단백질 연구에 활용됩니다.

제품 정보

배경 정보

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012]