ELK Biotechnology EST3 rabbit pAb
Human EST3 단백질을 인식하는 rabbit polyclonal antibody로, WB 실험에 적합합니다. 인간, 랫, 마우스에 반응하며, 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
EST3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Carboxylesterase 3 (EC 3.1.1.1), Liver carboxylesterase 31 homolog |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human EST3 (AA range: 447–497) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 65 kD |
| GeneID (Human) | 23491 |
| Human Swiss-Prot No | Q6UWW8 |
| Cellular Localization | Endoplasmic reticulum lumen |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system.
This gene is expressed in several tissues, particularly in colon, trachea, and brain, and the protein participates in colon and neural drug metabolism.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.
[provided by RefSeq, Jun 2010]
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