ELK Biotechnology H2AB1 rabbit pAb
H2AB1 단백질을 인식하는 토끼 폴리클로날 항체로, WB에 사용 가능. 인간 및 생쥐 시료 반응성. 핵 내 염색체 관련 단백질 연구에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology H2AB1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | H2AB1 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human H2AB1 (AA range: 49–99) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 474382 |
| Human Swiss-Prot No. | P0C5Y9 |
| Cellular localization | Nucleus, Chromosome. Associated with the active X chromosome and autosomes; absent from the inactive X chromosome and excluded from Barr bodies. |
| Species Reactivity | Human, Mouse |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction with a linker histone (H1), forming higher-order chromatin structures.
This gene encodes a replication-independent histone that is part of the histone H2A family. It is located in a region repeated three times on chromosome X: once in intron 22 of the F8 gene and twice near the Xq telomere. This record represents the most centromeric copy, located in intron 22 of the F8 gene. (RefSeq, Oct 2015)
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