Thermo Fisher Scientific SYTL5 Polyclonal Antibody
Thermo Fisher Scientific의 SYTL5 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 SYTL5 단백질 검출에 사용됩니다. Western blot과 IHC에 적합하며, 항원 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the amino terminus of human SYTL5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157463 |
Product Specific Information
- A suggested positive control is HeLa cell lysate.
- PA5-21176 can be used with blocking peptide PEP-1290.
Target Information
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus.
The SHD functions as a binding site for Rab27A, which plays a role in protein transport.
Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues.
Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration.
SYTL7 and SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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