Thermo Fisher Scientific CFHR5 Polyclonal Antibody
인간 CFHR5 단백질을 인식하는 염소 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 5 (CFHR5) Glu19–Glu569 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605660 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The CFHR5 gene belongs to the complement factor H (CFH) gene cluster on chromosome 1. Members of this family contain multiple short consensus repeats (SCRs) typical of complement activation regulators. The encoded protein has nine SCRs: the first two have heparin binding properties, repeats 5–7 bind heparin and C-reactive protein, and the C-terminal repeats resemble the complement component 3b (C3b) binding domain. CFHR5 co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Variations in this gene have been associated with membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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