Thermo Fisher Scientific GPX1 Monoclonal Antibody (K.163.2)

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins that catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. Several isoforms differ in primary structure and localization:

• GPx1 (cGPx): Classical cytosolic/mitochondrial, selenium-dependent enzyme.
• GPx2 (GI-GPx): Expressed in gastrointestinal epithelium.
• GPx3 (pGPx): Extracellular plasma enzyme expressed by the kidney and released into blood.
• GPx4 (PH-GPx): Reduces various hydroperoxides, including membrane-integrated hydroperoxides and lipid peroxides.
• Other isoforms (GPx3, GPx5) may contain cysteine instead of selenocysteine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.