Thermo Fisher Scientific Bestrophin 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:400

-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Bestrophin 2, amino acids 101-200. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Bestrophin 2,uniProtId:Q8NFU1-1,ncbiNodeId:9606,antigenRange:101-200,antigenLength:509,antigenImageFileName:BS-11041R_Bestrophin_2_Q8NFU1-1_Rabbit.svg,antigenImageFileNamePDP:BS-11041R_Bestrophin_2_Q8NFU1-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3` ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.