Thermo Fisher Scientific Phospho-GDF9 (Tyr394) Polyclonal Antibody

Applications and Tested Dilution

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human GDF9 (Accession O60383), corresponding to amino acid residues around phosphorylated Tyr394.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Sequential chromatography

Storage Buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage Conditions

-20°C

Shipping Conditions

Wet ice

RRID

AB_2816738

Product Specific Information

This antibody detects endogenous levels of GDF9 only when phosphorylated at Tyr394.

Target Information

GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. These proteins contain a polybasic proteolytic processing site that is cleaved to produce a mature protein with seven conserved cysteine residues. Members of this family regulate cell growth and differentiation in embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is essential for ovarian folliculogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.