Thermo Fisher Scientific GIT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GIT1. Recombinant protein control fragment (Product #RP-102396). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GIT1,uniProtId:Q9Y2X7-1,ncbiNodeId:9606,antigenRange:535-670,antigenLength:761,antigenImageFileName:PA5-82131_GIT1_Q9Y2X7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82131_GIT1_Q9Y2X7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789292

Product Specific Information

Immunogen sequence: HSTELEDDAI YSVHVPAGLY RIRKGVSASA VPFTPSSPLL SCSQEGSRHT SKLSRHGSGA DSDYENTQSG DPLLGLEGKR FLELGKEEDF HPELESLDGD LDPGLPSTED VILKTEQVTK NIQELLRAAQ EFKHDS

Target Information

GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.