Thermo Fisher Scientific IARS2 Polyclonal Antibody
인간 IARS2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A305-640A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IARS2 Polyclonal Antibody
Thermo Fisher Scientific IARS2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 20 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 962 to 1012 of human Isoleucyl-tRNA synthetase, mitochondrial |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, associated with genetic alterations and thyroid hormone response abnormalities. Trip230 interacts with Rb and thyroid hormone receptor (TR) through distinct domains. Complex formation with Rb occurs in a hormone-independent manner, while with TR it is thyroid hormone-dependent. After T3 treatment, Trip230 is phosphorylated and translocated to the nucleus, indicating phosphorylation’s role in nuclear transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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