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Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI3C2), TrueMAB
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Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI3C2), TrueMAB

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CRYAB 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, WB, IHC, Flow, IP 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태. 인간 시료 반응성, 연구용으로만 사용.

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pk
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Thermo Fisher Scientific TA500573 CRYAB Monoclonal Antibody (OTI3C2), TrueMAB 100 ul pk판매 단위 pk
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI3C2), TrueMAB

Thermo Fisher Scientific CRYAB Monoclonal Antibody (OTI3C2), TrueMAB

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:1,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:50
Flow Cytometry (Flow) 1:100
Immunoprecipitation (IP) 2 µg/500 µL

Product Specifications

Specification Description
Species Reactivity Human
Host/Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI3C2
Immunogen Full length human recombinant protein of human CRYAB produced in HEK293T cells
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index. The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma.
Alpha-crystallin is composed of two primary gene products, alpha-A and alpha-B, and comprises 40% of total lens protein composition. It functions as a molecular chaperone preventing aggregate formation that may lead to cataract development. Phosphorylation of alpha-crystallin occurs in response to cellular stress and may play a role in protein maintenance.
Alpha-B crystallin has been linked to Alexander’s disease, where it accumulates in brain cells of affected individuals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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