Thermo Fisher Scientific C. rhodostoma Snaclec rhodocytin subunit alpha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Product Specifications

Species Reactivity

Reptile

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136aa)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.609 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2902352

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.