
Thermo Fisher Scientific LAMTOR3 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:100
Immunocytochemistry (ICC/IF)
1:50
Product Specifications
Species Reactivity
Human, Mouse
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A genomic peptide made to an internal region of the human MAP2K1IP1/MAPKSP1 protein (within residues 20-180). [Swiss-Prot Q9UHA4]
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1.08 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718809
Target Information
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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