Thermo Fisher Scientific PKP3 Polyclonal Antibody
PKP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC 및 ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태로 안정적인 장기 보관 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PKP3. Recombinant protein control fragment (Product #RP-104169) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791725 |
Product Specific Information
Immunogen sequence:
FDDIDLPSAV KYLMASDPNL QVLGAAYIQH KCYSDAAAKK QARSLQAVPR LVKLFNHANQ EVQRHATGAM RNLI
Target Information
Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. Its expression is largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctate staining pattern typical for desmosomal proteins. In addition to desmosomal localization, bright nuclear speckles are observed. Like plakophilin-1 and -2, plakophilin-3 shows dual localization in the desmosomal plaque and nucleus, suggesting involvement in signal transduction between the plasma membrane and nucleus. The human protein has a predicted molecular mass of approximately 87 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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