Thermo Fisher Scientific VASP Monoclonal Antibody (OTI4D6), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family.
These proteins contain an EHV1 N-terminal domain that binds E/DFPPPPXD/E motif-containing proteins and targets Ena-VASP proteins to focal adhesions.
The mid-region includes a proline-rich domain binding SH3 and WW domain-containing proteins, while the C-terminal EVH2 domain mediates tetramerization and binds both G and F actin.
VASP is associated with filamentous actin formation and plays a key role in cell adhesion and motility.
It may also participate in intracellular signaling pathways regulating integrin–extracellular matrix interactions.
Regulated by cyclic nucleotide-dependent kinases PKA and PKG.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.