
Thermo Fisher Scientific SMC1 Polyclonal Antibody
Rabbit 폴리클로날 항체로 SMC1 단백질을 인식합니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능하며, 4°C에서 보관합니다. 인간 SMC1의 C-말단 영역을 면역원으로 사용하였으며, Rat 및 Bovine에도 반응 예측됩니다.
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Thermo Fisher Scientific SMC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 and the C-terminus of Human Structural Maintenance of Chromosomes 1 (SMC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events requiring structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion during mitosis.
Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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