Thermo Fisher Scientific MDC1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human MDC1. Validated for WB, IHC, and IP applications. Supplied as a liquid at 1 mg/mL, stored at 4°C. Suitable for DNA damage response research.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:25,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1375 and 1425 of human Mediator of DNA Damage Checkpoint 1 (MDC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee
Target Information
MDC1 participates in the early response to DNA damage. It is a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. MDC1 contains an N-terminal forkhead-associated (FHA) motif, two C-terminal BRCT motifs, and 13 internal repetitions of a 41 amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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