Thermo Fisher Scientific TRPML3 Polyclonal Antibody
TRPML3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. IHC(P)에서 1:200~1:500 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보존되어 장기 보관 시 -20°C에서 안정적입니다.
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- PA564006
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Mucolipin 3. Recombinant protein control fragment (Product #RP-103436) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644302 |
Product Specific Information
Immunogen sequence:
KGYMDRMDDT YAVYTQSDVY DQLIFAVNQY LQLYNVSVGN HAY
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 86%
Target Information
Expressed in the cochlea, particularly in the inner and outer hair cells.
Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities, and perinatal lethality.
The varitin-waddler Jackcon (Va-J) phenotype, which arose in a cross segregating for Va, is similar but less severe.
Belongs to the transient receptor family, polycystin subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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