Thermo Fisher Scientific BCL6 Monoclonal Antibody (PCRP-BCL6-1E2)
인간 BCL6 단백질을 인식하는 Mouse IgG2b 단클론 항체로, ICC/IF, Flow Cytometry, Peptide Array 등 다양한 응용에 적합합니다. Protein A/G로 정제된 액상 형태이며, PBS buffer에 보존되어 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | References |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | - |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-BCL6-1E2 |
| Immunogen | Recombinant full-length human BCL6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and Bcl-6 rearrangements have been detected in 33%–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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