Thermo Fisher Scientific NDST1 Polyclonal Antibody
Rabbit polyclonal antibody against human NDST1 for Western blot applications. Antigen affinity purified, supplied as liquid in PBS with sodium azide. Detects NDST1 involved in heparan sulfate biosynthesis. For research use only.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NDST1 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human NDST1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890335 |
Product Specific Information
Positive controls that may be used include: U937 Cell Lysate
Target Information
NDST1 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and N-sulfation of glucosamine (GlcNAc) residues in heparan sulfate. It modifies the GlcNAc-GlcA disaccharide backbone to produce N-sulfated heparosan, a key intermediate in heparin biosynthesis. NDST1 determines the extent and pattern of sulfation in heparan sulfate and is required for biosynthesis of heparan sulfate that can act as L-selectin ligands, contributing to inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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