Thermo Fisher Scientific CPS1 Polyclonal Antibody
CPS1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Protein A 정제 및 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human CPS1 (amino acids 1351–1500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The mitochondrial enzyme encoded by the CPS1 gene catalyzes the synthesis of carbamoyl phosphate from ammonia and bicarbonate, representing the first committed step of the urea cycle. This process is crucial for the removal of excess urea from cells. The encoded protein may also serve as a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been identified; the shortest isoform may not localize to the mitochondrion. Mutations in CPS1 are associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and venoocclusive disease following bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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