Thermo Fisher Scientific MTHFD1 Polyclonal Antibody
Thermo Fisher Scientific의 MTHFD1 Polyclonal Antibody는 인간, 생쥐, 랫드 반응성을 가진 Rabbit IgG 기반 항체입니다. Western blot, ICC/IF, ELISA에 적합하며 고순도 Affinity chromatography로 정제되었습니다. 안정적인 액상 형태로 -20°C에서 보관 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–270 of human MTHFD1 (NP_0059473) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.16 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901777 |
Product Specific Information
Positive Samples: Raji, LO2, Mouse brain, Mouse kidney, Rat spinal cord
Immunogen Sequence:
MAPAEILNGK EISAQIRARL KNQVTQLKEQ VPGFTPRLAI LQVGNRDDSN LYINVKLKAA EEIGIKATHI KLPRTTTESE VMKYITSLNE DSTVHGFLVQ LPLDSENSIN TEEVINAIAP EKDVDGLTSI NAGKLARGDL NDCFIPCTPK GCLELIKETG VPIAGRHAVV VGRSKIVGAP MHDLLLWNNA TVTTCHSKTA HLDEEVNKGD ILVVATGQPE MVKGEWIKPG AIVIDCGINY VPDDKKPNGR KVVGDVAYDE AKERASFITP
Target Information
This gene encodes a protein that possesses three distinct enzymatic activities:
- 5,10-methylenetetrahydrofolate dehydrogenase
- 5,10-methenyltetrahydrofolate cyclohydrolase
- 10-formyltetrahydrofolate synthetase
Each activity catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses.
The trifunctional enzymatic activities are conferred by two major domains: an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities, and a larger synthetase domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-117147_MTHFD1_P11586-1_Rabbit.svg, PA5-117147_MTHFD1_P11586-1_Rabbit_PDP.jpeg)
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