Thermo Fisher Scientific Histone H2B Polyclonal Antibody
Histone H2B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 등에 적합합니다. Human, Mouse, Rat에 반응하며 고순도(>95%)로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids at the N-terminus of Human Histone H2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803317 |
Product Specific Information
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). These nucleosomes further compact DNA into chromatin, limiting DNA accessibility to cellular machineries that require DNA as a template. Histones play central roles in transcription regulation, DNA repair, replication, and chromosomal stability. H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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