Thermo Fisher Scientific TLK2 Polyclonal Antibody
TLK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 인간과 마우스 시료에서 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol 용액 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TLK2 (Accession Q86UE8), corresponding to amino acid residues Q331–E381 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851301 |
Product Specific Information
This antibody detects endogenous levels of total TLK2.
Target Information
TLK2 (Tousled-like kinase 2) is a nuclear serine/threonine kinase involved in chromatin assembly regulation and other cellular processes such as intracellular signaling, protein phosphorylation, cell cycle progression, chromatin modification, and response to DNA damage. TLK2 activity peaks during the S phase and is regulated by cell cycle-dependent phosphorylation. It becomes inactivated upon DNA replication inhibition, indicating a close link to replication. TLK2 forms heterodimers with TLK1 and is widely expressed in fetal and adult tissues including placenta, liver, kidney, pancreas, heart, and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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