Thermo Fisher Scientific REA Polyclonal Antibody
Thermo Fisher Scientific의 REA Polyclonal Antibody는 Rabbit IgG 기반의 비결합 항체로 Western blot에 적합합니다. 인간 REA 중간 영역 합성 펩타이드로부터 유래되었으며, PBS와 2% sucrose buffer에 보관됩니다. 다양한 종에서 높은 상동성을 보입니다.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human REA (aa 191–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690275 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 93%.
Immunogen is a synthetic peptide located within the following region:
REYTAAVEAK QVAQQEAQRA QFLVEKAKQE QRQKIVQAEG EAEAAKMLGE
Target Information
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.
This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.
It competes with NCOA1 for modulation of ER transcriptional activity.
It is probably involved in regulating mitochondrial respiration activity and in aging.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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