Thermo Fisher Scientific Cyclin T2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Cyclin T2. Recombinant protein control fragment (Product #RP-102477). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cyclin T2,uniProtId:O60583-1,ncbiNodeId:9606,antigenRange:413-551,antigenLength:730,antigenImageFileName:PA5-52163_Cyclin_T2_O60583-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52163_Cyclin_T2_O60583-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640309

Product Specific Information

Immunogen sequence: KAGSSKHHGP ISTTPGIIPQ KMSLDKYREK RKLETLDLDV RDHYIAAQVE QQHKQGQSQA ASSSSVTSPI KMKIPIANTE KYMADKKEKS GSLKLRIPIP PTDKSASKEE LKMKIKVSSS ERHSSSDEGS GKSKHSSPH

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

Target Information

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.