Thermo Fisher Scientific AMT Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AMT. Recombinant protein control fragment (Product #RP-88771). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AMT,uniProtId:P48728-1,ncbiNodeId:9606,antigenRange:60-180,antigenLength:403,antigenImageFileName:PA5-52166_AMT_P48728-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52166_AMT_P48728-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637920

Product Specific Information

Immunogen sequence: QYRDSHTDSH LHTRQHCSLF DVSHMLQTKI LGSDRVKLME SLVVGDIAEL RPNQGTLSLF TNEAGGILDD LIVTNTSEGH LYVVSNAGCW EKDLALMQDK VRELQNQGRD VGLEVLDNAL L

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 64%.

Target Information

The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.