Thermo Fisher Scientific AMT Polyclonal Antibody
AMT 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 버퍼에 보관. 인간 시료에 반응하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AMT. Recombinant protein control fragment (Product #RP-88771) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637920 |
Product Specific Information
Immunogen sequence:
QYRDSHTDSH LHTRQHCSLF DVSHMLQTKI LGSDRVKLME SLVVGDIAEL RPNQGTLSLF TNEAGGILDD LIVTNTSEGH LYVVSNAGCW EKDLALMQDK VRELQNQGRD VGLEVLDNAL L
Sequence identity (orthologs):
- Mouse: 88%
- Rat: 64%
Target Information
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of four protein components:
- P protein: Pyridoxal phosphate-dependent glycine decarboxylase
- H protein: Lipoic acid-containing protein
- T protein: Tetrahydrofolate-requiring enzyme
- L protein: Lipoamide dehydrogenase
Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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