Thermo Fisher Scientific STUB1 Polyclonal Antibody
STUB1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등에 사용 가능. 인간, 마우스, 랫트에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 버퍼에 보관되며, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 17–303 of Human STUB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549519 |
Product Specific Information
- Recommended positive controls: 293T, A431, Raji, BT-474, HCC1937, Hs578T, MCF7, MDA-MB-231, MDA-MB-361, MDA-MB-453, T-47D, ZR-75-1, HeLa, U2OS
- Predicted reactivity: Mouse (97%), Rat (97%), Chicken (87%), Rhesus Monkey (100%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The carboxyl terminus of hsc70-interacting protein (CHIP) interacts with both constitutive hsc70 and inducible hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and various cultured tissues. CHIP binds to the carboxyl terminus of hsc70 and hsp70, decreasing ATPase activity and chaperone efficiency. It functions as an E3 ubiquitin-ligase within the ubiquitin-proteasome system through its U-box domain.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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