Thermo Fisher Scientific PRDM1 Monoclonal Antibody (1F2)
PRDM1 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체. Western blot과 ELISA에 적합하며, 인간 단백질에 반응. PRDM1의 전장 재조합 단백질로부터 유래된 항원 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F2 |
| Immunogen | PRDM1 (NP_001189, 422 a.a. approximately 493 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
HPMLNPTSLP SSLPSDGARR LLQPEHPREV LVPAPHSAFS FTGAAASMKD KACSPTSGSP TAGTAATAEH V
Target Information
Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It functions as a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for, terminally differentiated epithelial cells, retinal neurons, and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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